Children Do Much Better in Math When Music is Added to the Lesson: New Study

Photos by Crissy Jarvis (left) and Ben Mullins

A new study explored the causal role that music engagement has on student achievement in mathematics—and they found a significant benefit. Researchers believe that music can make math more enjoyable, keep students engaged, and help ease their fear or anxiety about topics like fractions. The addition of music may even motivate kids to appreciate math and want to learn more. A typical technique for integrating music into math lessons for young children involves clapping to songs with different rhythms learning numbers, and equating fractions to musical notes. The new meta-analysis published in the journal Educational Studies analyzed 55 studies from around the world, involving almost 78,000 students, from kindergarten to university age. Three types of musical interventions were included: typical music lessons in which children sing, listen to, and learn about composing music; learning how to play instruments alone or as part of a band; and music-math integrated interventions, where music was integrated into math lessons. Students took math tests before and after taking part in the intervention, and the change in their scores was compared with those who didn’t take part in any intervention. The use of music—whether in separate lessons or as part of math classes—caused a greater improvement in math over time. Combining both in the same lessons had the most significant effect, with around 73 percent of students who had integrated lessons doing significantly better than children who didn’t have any type of musical intervention. Also, 69 percent of students who learned how to play instruments and 58 percent of students who had normal music lessons improved more than pupils with no musical intervention. The results also revealed that music helps more with learning arithmetic than other types of math and has a bigger impact on younger pupils and those learning basic mathematical concepts. Math and music have much in common, such as the use of symbols and symmetry. Both subjects also require abstract thought and quantitative reasoning. Arithmetic may lend itself particularly well to being taught through music because core concepts, such as fractions and ratios, are also fundamental to music. Musical notes of different lengths can be represented as fractions and added together to create several bars of music. Integrated lessons may be especially effective because they allow pupils to build connections between the math and music and provide extra opportunities to explore, interpret and understand math. “Encouraging mathematics and music teachers to plan lessons together could help ease students’ anxiety about mathematics, while also boosting achievement,” said Dr. Ayça Akın, from the department of software engineering at Antalya Belek University, Turkey. However, she said there were limitations to the study. The relatively small number of studies done meant it wasn’t possible to look at the effect of variables such as gender, socio-economic status, and duration of musical instruction upon the results. Children Do Much Better in Math When Music is Added to the Lesson: New Study

Read More........→April 16, 2024

Scientists Discover Potential HIV Cure that Eliminates Disease from Cells Using CRISPR-Cas Gene Editing

HIV-1 virus particles under electron micrograph with H9 T-cells (in blue) – Credit: National Institute of Allergy and Infectious Diseases

A new study has unveiled a likely future cure for HIV which uses molecular scissors to ‘cut out’ HIV DNA from infected cells. To cut out this virus, the team used CRISPR-Cas gene editing technology—a groundbreaking method that allows for precise alterations to a patient’s genome, for which its inventors won the Nobel Prize in Chemistry in 2020. One of the significant challenges in HIV treatment is the virus’s ability to integrate its genome into the host’s DNA, making it extremely difficult to eliminate—but the CRISPR-Cas tool provides a new means to isolate and target HIV DNA. Because HIV can infect different types of cells and tissues in the body, each with its own unique environment and characteristics, the researchers are searching for a way to target HIV in all of these situations. In this study, which is to be presented ahead of this year’s European Congress of Clinical Microbiology and Infectious Diseases, the authors used CRISPR-Cas and two guide RNAs against “conserved” HIV sequences. They focused on parts of the virus genome that stay the same across all known HIV strains and infected T cells. Their experiments showed outstanding antiviral performance, managing to completely inactivate HIV with a single guide RNA and cut out the viral DNA with two guide RNAs. “We have developed an efficient combinatorial CRISPR-attack on the HIV virus in various cells and the locations where it can be hidden in reservoirs, and demonstrated that therapeutics can be specifically delivered to the cells of interest,” said Associate professor Elena Herrera Carrillo from the University of Amsterdam AMC. “These findings

HIV AIDS virus (in yellow) infecting a human cell – Credit: National Cancer Institute

represent a pivotal advancement towards designing a cure strategy.” The team has a long way to go before their cure will be available to patients, but said, “These preliminary findings are very encouraging’. Currently, HIV can be kept in check with anti-retroviral medication, but no one has actually been cured—although three patients receiving stem cell transplants for blood cancer were subsequently declared free of the disease when their HIV became undetectable. “We hope to achieve the right balance between efficacy and safety of this CURE strategy,” said Dr. Carrillo. “Only then can we consider clinical trials of ‘cure’ in humans to disable the HIV reservoir.“Our aim is to develop a robust and safe combinatorial CRISPR-Cas regimen, striving for an inclusive ‘HIV cure for all’ that can inactivate diverse HIV strains across various cellular contexts. Scientists Discover Potential HIV Cure that Eliminates Disease from Cells Using CRISPR-Cas Gene Editing

Read More........→March 26, 2024